CBD News

CBD For Bone Growth

CBD for Bone Growth from That's Natural, V2

That’s right. CBD may promote bone growth and healing! Be it a broken bone, or something else, CBD may be solution you need!

The Journal of Bone and Mineral Research published a study regarding CBD and it’s ability to enhance fracture healing and stimulate lysyl hydrozylase activity in osteoblasts. Cannabinoid ligands help regulate bone mass. With over 6.3 million bone fractures a year, the following research is very promising for those suffering from one. Although they all vary in severity and placement, one thing they almost all share is immobilization and discomfort.

One of the most more serious bone fractures are femoral fractures. This study from the Journal of Bone and Mineral Research reports that CBD enhances certain biomechanical properties of healing rat mid-femoral fractures. CBD was shown to increase the maximal load and work-to-failure, but not the stiffness of femurs. Tetrahydrocannabinol (THC) did not share this effect.

Using micro-computed tomography, CBD was shown to transiently reduce the fracture callus size after just four weeks, but took 6-8 weeks to reach control level. The density of the callus material was not effected.

Lysine hydroxylation is involved in collagen crosslinking and stabilization. So, what does CBD have to do with lysine hydroxylation? “CBD stimulated mRNA expression of Plod1 in primary osteoblast cultures, encoding an enzyme that catalyzes lysine hydroxylation”. CBD was shown to also increase the collagen crosslink ratio, which is believed to contribute to the improved biomechanical properties of the fracture callus.

The study concluded by stating: “Taken together, these data show that CBD leads to improvement in fracture healing and demonstrate the critical mechanical role of collagen crosslinking enzymes.”

Although there is more research needed to conclusively state whether CBD helps with these issues, this anecdotal research is a great step in the right direction.


That’s Natural products are considered to be full spectrum meaning they contain cannabinoids and terpenes from the whole plant. Every mammal has an endocannabinoid system,  which is fueled by these cannabinoids and terpenes.   The combination of these compounds help to provide what is known as the entourage effect. Here you can listen to Dr. David Allen explain how the endocannabinoid system contributes to how our immune system and nervous system function.  By providing pure, potent, and trusted products, That’s Natural continues to strive to meet our customer’s needs – something we have been doing for twelve years! With 100% traceability of where our hemp comes from, you can be confident in what you are putting on, or in, your body. For more questions regarding our CBD products, please visit our Questions and Answers page.


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