CBD News

Topical Administration of CBD Can Reduce Pain

Topical administration of CBD can help to reduce pain!  See more from That’s Natural at www.cbdoil.life and @cbdhempoil #skin #skincare #spas #spaday #psoriasis #eczema #beauty #health #alternative #wellness #mom #life #holistic #healing #essentialoils #wellnessjourney #wellness #sports #sportsmedicine #ThatsNatural

Many people wonder about using Cannabidiol (CBD) topically instead of ingesting an oil. However, some question whether it would work as well as ingesting it. Others prefer to use a lotion/crème because of the experience. Fortunately there are many benefits to using CBD topically – especially for pain relief. For molecules to be absorbed trans dermally, they must be under 500 g/mol. CBD only measures at 314.469 g/mol.

– CBD can be applied directly to the painful areas, which means it may work faster and more efficiently. This also means that analgesic effects are more concentrated to the areas that truly need it.  See this study.

– Zero drugs interactions are known – which means there is no risk of mixing other medications with a topical CBD product.

– CBD can be applied as needed, without any risk of “abuse”.

While some of these make sense, some of them are a bit more confusing. If someone is hurting in a specific area, it makes sense to apply a lotion/crème to that specific area for relief. It reduces the amount of energy the body uses to circulate the CBD throughout our different body systems. When applied topically, the CBD is also not “lost” in parts of the body that don’t necessarily need it.

So, does it really work? Well, according to this study from the National Institutes of Health, yes. The study found that CBD and cannabinol (CBN) yield analgesia by acting at perhipheral sites because of the action on CB1 and CB2 receptors. In fact, Dorsal root ganglia cells contain mRNA for CB1 receptors.

“Additionally, CB1 receptor agonists inhibit nerve growth factor and calcitonin gene-related peptide release.71 Local analgesic actions of agonists for CB2 receptors include the inhibition of mast cell function and inflammatory pain.

The topical administration of selective cannabinoid receptor agents has been demonstrated to have analgesic effects in animal models of inflammatory and neuropathic pain (formalin, carrageenan hyperalgesia, and partial nerve injury), especially for the control of breakthrough pain.”

Also, because no known drug interactions have been found to topical applications of CBD, it may be something more people are willing to try. The evidence is strong that CBD can help with a lot of skin issues including: Acne, psoriasis, cancer, allergic dermatitis, itch and pain, and even hair growth disorders.


Because That’s Natural products contain numerous cannabinoids and terpenes it is considered full spectrum. The combination of these compounds help to provide what is known as the entourage effect. Each one of us (and our animals) has an endocannabinoid system,  which is fueled by these cannabinoids and terpenes to produce the entourage effect. By providing pure, potent, and trusted products, That’s Natural strives to meet our customer’s needs – something we have been doing for over ten years! With 100% traceability of where our hemp comes from, you can be confident in what you are putting on, or in, your body. For more questions regarding our CBD products, please visit our Questions and Answers page.

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